Natural Selection, Inc.^® Publishes RNA Structure Similarity Application of Evolutionary Algorithms in NucleicAcids Research

La Jolla, CA -- Dr. Gary B. Fogel, Senior Staff Scientist, Vincent W. Porto, Executive Vice President, Dana Weekes, Staff Scientist, and Dr. David B. Fogel, Chief Executive Officer of Natural Selection, Inc.^®, in collaboration with researchers at Ibis Therapeutics (Carlsbad, CA) have published a paper titled "Discovery of RNA Structural Elements Using Evolutionary Computation" in the journal Nucleic Acids Research (Vol. 30:5310-5317). This new research highlights the application of evolutionary computation towards the analysis of biochemical sequence information for the assignment of structural folding similarity. Results indicated that the method could be used to search very large sets of possible RNA structures for similarity over wide ranges of phylogenetic distance. Using this method, the RNA structure for the signal recognition particle was identified in two newly sequenced bacteria. To obtain a copy of the publication, please email Dr. Gary Fogel at gfogel [at] natural-selection.com. 

Natural Selection, Inc.^® was founded in 1993 to address complex problems in industry, medicine, and defense. The company possesses unique expertise in computational intelligence techniques, including evolutionary computation, neural networks, and fuzzy logic. The corporation's research efforts support the discovery of new pharmaceuticals, the automated detection and diagnosis of breast cancer from film-screen mammograms, optical character recognition, and a variety of military and industrial projects.

For more information, please contact:

Dr. David B. Fogel,
Chief Executive Officer,
Natural Selection, Inc.,
3333 N. Torrey Pines Ct.,
Suite 200,
La Jolla, CA, 92037
tel: (858) 455-6449
fax: (858) 455-1560
dfogel [at] natural-selection.com