Natural Selection, Inc.^® Publishes Biochemical Application of Evolutionary Algorithms in BioSystems

La Jolla, CA -- Dana Landavazo, staff scientist, Dr. Gary B. Fogel, senior staff scientist, and Dr. David B. Fogel, chief executive officer of Natural Selection, Inc., have published a paper titled "Quantitative structure-activity relationship by evolved neural networks for the inhibition of dihydrofolate reductase by pyrimidines" in the journal BioSystems (Vol. 65:37-47). This new research indicates a potential advance in the application of evolved neural networks for the development of better structure-activity relationship models. Results indicated that the performance of evolved neural networks for developing statistical models relating drug structure to activity can outperform classical neural network training methods such as backpropagation. To obtain a copy of the publication, please email Dr. Gary Fogel at: gfogel [at] natural-selection.com.

Natural Selection, Inc.^® was founded in 1993 to address complex problems in industry, medicine, and defense. The company possesses unique expertise in computational intelligence techniques, including evolutionary computation, neural networks, and fuzzy logic. The corporation's research efforts support the discovery of new pharmaceuticals, the automated detection and diagnosis of breast cancer from film-screen mammograms, optical character recognition, and a variety of military and industrial projects.

For more information, please contact:

Dr. David B. Fogel,
Chief Executive Officer,
Natural Selection, Inc.,
3333 N. Torrey Pines Ct.,
Suite 200,
La Jolla, CA, 92037
tel: (858) 455-6449
fax: (858) 455-1560
dfogel [at] natural-selection.com